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- "Blood Harvest: The Tunnel": Easy win as Infected
In Versus mode, there is a warehouse-type area immediately after the starting safe room. As a zombie, quickly run back to the emergency door on the other side of the warehouse. There should be a forklift near the door. Spawn and push this forklift in front of the doorway. Note: You may need to break the white door in front of the emergency door to get the forklift all the way in front of the doorway.
- "Dead Air: The Construction Site": Shortcut
In "The Construction Site", there is a metal door and a raised fence by the barricade that you burn. Jump on the fence and follow it until it begins to go downward. At this point, jump on the metal siding "door". Note: Some practice may be required.
- "Dead Air: The Crane": Shortcut
In "The Crane", jump on the fence after climbing on the vent cover. Go across the fence then jump to the other side of the horizontal fence. Turn left and go to the end. Jump up and to the right to air conditioning unit box on the corner of the next building. Once on the next building, go to the left corner. Jump to the top branch of the tree below you. You will lose a lot of health after landing. However you will be at the next safe room.
- "Death Toll: Boathouse": Items
Under any difficulty setting, a health pack and pills will spawn in the bathroom across the field from the house.
- "No Mercy: The Apartments": Easy kills
In level 1 of the No Mercy chapter, the Survivors must jump into a sewer hole to enter them. As an Infected, use this to your advantage. One must be a Smoker or a Hunter. Do not spawn; instead hide behind one of the large canisters in the room. Once the players open the hole and are done checking the vicinity, they will jump in. Due to the fact they must jump in one at a time or get stuck, make sure you have a clear view of the last one in line. Once all three are down and the fourth Survivor is still up, pounce or grab him. By doing this he will not be able to be saved, unless someone throws a Molotov or a pipe bomb.
- "No Mercy: The Apartments": Shortcut
As soon as the level starts, look over the edge of the building and down to the street. Notice the box-like object that is partway down. Drop down to it. Although you will take some damage, you will still be alive. You can then drop down to ground level and continue the level.
- "No Mercy: The Hospital": Easy win as Infected
Before you spawn, go all the way up to floor 28, where the elevator lets out. Just outside of the elevator is a generator. Move it in front of the elevator door. , if the Survivors know what you are doing, they can move it. It will require three survivors to move an object. However if you have someone else on the Infected side, they can go a little bit further and move the forklift that is there in front of the doorway.
- "No Mercy: The Sewer": Easy way through
Over by the trucks is a door that you can open later. However if you have some people meleeing it, it will eventually break.