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Better use of skillpoints
In fallout all skills are derived from stats. If you change a stat all skills that use that stat are changed to. If you want to increase a skill more than 101 it costs more than 1 point for +1 in skill.
Here is the nice thing about this, and ill use SCIENCE as example.
If you have 8 Intelligense and have increased Sciense to 101, then 102 vould cost 2 skillpoints to get. If you take a mentat(be carefull not to gett addicted) your Inteligense will raise to 10 for a while. After a few hours (use the pip-boy) you will go into withdrawl where your Int goes down by 3 ending on 7, this will lower your Science skill by a few points. Now you can increase the skill for a lower cost of skillpoints.
This works for all skills but Gamble, there are no drugs for Luck.
So save all the mentats/jet/buffout/psycho you come across, the can save you skillpoints.